Pomeranian (detail introduction)
Activirus (CCV) is an acute intestinal infectious disease that can infect dogs of various ages. It mainly manifests in symptoms such as vomiting, diarrhea, anorexia.
1. Pathogen
Coronary virus is a single -chain RNA virus with cystic membrane. Its antigenicity is related to the coronary virus (cat infectious peritonitis virus and cat intestinal coronary virus) and pig infectious gastroenteritis virus. The virus is sensitive to liquid solvents and most disinfectants. Coronary virus has a close relationship with pig infectious gastroenteritis virus in serum. Although the coronary virus does not be infected with pigs, pig infectious gastroenteritis virus can make dog clinical infections. Coronatte virus and cat infectious peritonitis virus and human coronary virus 229E also have related antigens. They together form a antigen group, but the canine coronary virus itself seems to have only one serum type. In addition, in recent years, coronary virus diarrhea often occurs in mink and ravioli and foxes. Symptoms are similar to that of canine coronal virus enteritis, but it is unclear whether they are related to antigenicity.
Second, pathogenic mechanism
Two days after the virus of this virus was exposed to the susceptible dog, it reached the upper part of the duodenum, which mainly infringed the digestive and absorption cells at 2/3 of the small intestinal velvet. The virus alleace drinks into the intestinal cells between the slightly velvet, and sprouts on the smooth membrane of the cytoplasm empty foam. Due to the rupture of the cell membrane, the virus enters the intestinal cavity with the infected cells that fall off, and then infects the fluffy epithelial cells of the entire intestine, and then the fluff is short and thick, the digestive enzyme and intestinal absorption function are lost, resulting in diarrhea. In the future, with the recovery of the small intestine structure, the clinical symptoms disappear, detoxification is reduced and terminated, and neutral antibodies are produced in serum.